Structural And Phytochemical Characterization of Bioactive Components of the Endophytic Fungi (Trichoderma harzianum) Extracts

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Date

2022

Journal Title

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Volume Title

Publisher

University of Port Harcourt

Abstract

This research aims to investigate the antioxidant activity of the crude extract of endophytic fungi (T. harzianum) and to test for the presence of phytochemicals. Fungi isolated from the leaf and stem of endemic medicinal plant were extracted with ethyl acetate. The fungi extract was then investigated for its phytochemicals, antioxidants and active compounds through LC-MS. Some of the phytochemicals present in abundance include saponins, alkaloids, flavonoids, phenols, and steroids, with tanins and cardiac glycosides also present in reasonable amounts. Those compounds identified by LC-MS with antioxidant properties include inosine diphosphate, vigabatrin, isoamylnitrite, proline, trihexyphenidyl-N-oxide, N-methyl gabapentin, penbutolol, dextromoramide M2, solanidine, aceclidine, desethyleneciproflaxin, sapropterin and kinetin.

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Keywords

Endophytic fungi, Trichoderma harzianum, antioxidants, phytochemicals, LC-MS

Citation

Ameen, O. M, Garuba, T., Zubair, M. F., Baker, M. T., Arowolo, B. Z. and Yakubu, A. O. (2022). Structural and phytochemical characterization of bioactive components of the endophytic fungi (Trichoderma harzianum) extracts. Journal of Applied Sciences and Environmental Management, 26 (4); 689-693.

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