Garlic consumption alters testicular histology and anti-oxidant status in Wistar rats.

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dc.contributor.authorOmotoso, Gabriel Olaiya
dc.contributor.authorOyewopo, AO
dc.contributor.authorOnanuga, Ismail Olashile
dc.contributor.authorEnaibe, BU
dc.date.accessioned2018-06-20T12:18:03Z
dc.date.available2018-06-20T12:18:03Z
dc.date.issued2012
dc.description.abstractGarlic is known for its cell and tissue-protective functions. This study examined the effects of aqueous garlic extract on the histology of the testes of Wistar rats and erythrocyte superoxide dismutase (SOD) activity. Twenty-four (24) rats with an average weight of 116 g were used. They were randomly grouped into three: Group A Control: was given distilled water; Group B: was given 500 mg/kg/d aqueous garlic extract; and Group C: received 1000 mg/kg/d aqueous garlic extract; all for 28 days. Findings revealed progressive depletion in sperm cell population, reduction in size of seminiferous tubules, and widening interstitial space. SOD activity was significantly reduced in both treated groups in a dose-dependent fashion. These histological observations and the depletion in endogenous anti-oxidant status associated with the administration of garlic could result in significant affectation of male reproductive functions.en_US
dc.identifier.citation19(2):31-33.en_US
dc.identifier.issn1117-4153
dc.identifier.urihttps://www.ajol.info/index.php/tjhc/article/view/81457
dc.identifier.urihttp://hdl.handle.net/123456789/692
dc.language.isoenen_US
dc.publisherThe Tropical Journal of Health Sciencesen_US
dc.subjectgarlicen_US
dc.subjectsuperoxide dismutaseen_US
dc.subjecttestesen_US
dc.subjecthistologyen_US
dc.titleGarlic consumption alters testicular histology and anti-oxidant status in Wistar rats.en_US
dc.typeArticleen_US

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