Antimicrobial activities of Bryophyllum pinnatum on some selected clinical isolates.

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dc.contributor.authorAnibijuwon, Ibikunle Ibiyemi
dc.contributor.authorSaliu, Bolanle Kudirat
dc.contributor.authorAbioye Jumai A
dc.contributor.authorGbala, Ife D.
dc.date.accessioned2024-05-03T14:50:30Z
dc.date.available2024-05-03T14:50:30Z
dc.date.issued2017
dc.description.abstractEthanol, methanol and aqueous extracts of the leaves of Bryophyllum pinnatum obtained through cold maceration, were screened for their antibacterial activities against selected multi-drug resistant bacteria (Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae, Salmonella typhi Staphylococcus aureus) using the agar well diffusion method. Broth dilution method was used to determine the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of the extracts at concentrations ranging from 100mg/ml to 25mg/ml. The ethanol extract was the most reactive while the aqueous extract showed lesser antibacterial activity. Ofloxacin was the most effective antibiotic in the antibiotic susceptibility profiling of the test organisms. It was however evident that the ethanol extract of Bryophyllum pinnatum has higher antibacterial efficacy on the test organisms than Ofloxacin. Bacteriostatic and -cidal activities were exhibited by the plant extracts against the organisms ranging from 25 – 100 × 103 μg/ml. Succinctly, Bryophyllum pinnatum possesses biologically active constituents with explorable pharmacological potentials.
dc.description.sponsorshipSelf with co-authors
dc.identifier.citationAnibijuwon, I.I., Saliu, B.K., Abioye, J.A., and Gbala I.D. (2017) Antimicrobial activities of Bryophyllum pinnatum on some selected clinical isolates. Fountain Journal of Natural and Applied Sciences. 6(1): 1–8. http://wwwfountainjournals.com/index.php/FUJNAS/article/view/22
dc.identifier.issn2354-337X
dc.identifier.urihttps://uilspace.unilorin.edu.ng/handle/123456789/13573
dc.language.isoen
dc.publisherPublished by Fountain University, Osogbo
dc.relation.ispartofseries6; 1
dc.subjectAntimicrobial
dc.subjectBryophyllum pinnatum
dc.subjectExtraction solvents
dc.subjectminimum inhibitory concentration (MIC)
dc.subjectminimum bactericidal concentration
dc.titleAntimicrobial activities of Bryophyllum pinnatum on some selected clinical isolates.
dc.title.alternativeFountain Journal of Natural and Applied Sciences.
dc.typeArticle

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