Phytochemical Analyses, Antimicrobial Activities and Possible Antimicrobial Mechanism of Adansonia Digitata: An Animal Model

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dc.contributor.authorOlutoyin C. Adekunle
dc.contributor.authorTemitope I. Adelusi
dc.contributor.authorIsmaila O. Sule
dc.contributor.authorAkanmidu R. Olorunfemi
dc.contributor.authorAbdulrahim Halimat A.
dc.contributor.authorAdeniran S. Adekunle
dc.date.accessioned2025-05-07T14:18:55Z
dc.date.available2025-05-07T14:18:55Z
dc.date.issued2022-07-01
dc.description.abstractThe advent of antibiotics recorded a huge amount of success against disease- causing microbes. However, development of resistance to reference antibiotics leading to increased mortality have caused critical concern in the management of infectious diseases. Continuous search for alternative therapies has shown good candidates in medicinal plants, although without thorough examination of possible mechanism of action. This study assessed the phytochemical constituents, antimicrobial activities, and possible antimicrobial mechanism of Adansonia digitata, against Shigella flexneri, Escerichia Coli and Salmonella enteritis. Phytochemical analyses showed that Adansonia digitata is rich phytosterols, flavonoids, phenolics and carotenoids. Assessments of antimicrobial activities of A. digitata revealed its effectiveness against S. flexneri, E. coli and S. enteritis. The mechanism of antimicrobial activities of A. digitata may involve inhibition of Gram+ and Gram- transpeptidase and dihydrofolate reductase. The antimicrobial activities may be ascribed to the presence of phytochemicals in A. digitata.
dc.identifier.citationAntimicrobial, vegetables, resistance, .microbes, mechanism
dc.identifier.issn1110-2047
dc.identifier.issnE-ISSN 2536-9520
dc.identifier.urihttps://uilspace.unilorin.edu.ng/handle/123456789/16386
dc.language.isoen
dc.publisherAlexandria Journal of Veterinary Sciences
dc.relation.ispartofseriesVol. 74 (2); 50-66
dc.titlePhytochemical Analyses, Antimicrobial Activities and Possible Antimicrobial Mechanism of Adansonia Digitata: An Animal Model
dc.typeArticle

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