A Cross-Sectional Study on Health-Related Quality of Life and Productivity Loss in HIV/AIDS Patients on ART
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2025
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Abstract
This study evaluated health-related quality of life (HRQoL), productivity loss, and associated factors among HIV/AIDS patients on antiretroviral therapy at a tertiary-level hospital in Ilorin, Kwara State, Nigeria. A cross-sectional study was conducted among patients registered in the clinic during the preceding ten years. Data were collected using the World Health Organization Quality of Life HIV Brief (WHOQOL-HIV-BREF) and the Work Productivity and Activity Impairment Questionnaire: General Health (WPAI:GH). Of the 358 participants, 94 (26.3%) were male and 264 (73.7%) females. Majority age group were 39-55years 204 (56%). Most respondents were married at 216 (60.3%) and did not perceive themselves as ill 334 (93.2). The overall (HRQoL) score was 59.34%, with 71.34% and 75.05% observed in the psychological and physical domains. Single individuals had increased scores of 30,25, 10 and 20 across HRQoL domains. Work impairment and overall activity impairment scores, as outcomes of work productivity, were found to be 12.81% and 14.35%, respectively. The highest percentage of patients (86.2 %) were on a Dolutegravir (DTG) based regimen, while others were on Atazanavir boosted regimens. Overall HRQol scores showed that participants were coping moderately well but had unmet needs due to chronic nature of the disease. Advanced medical care positively impacts the physical and psychological domains of HRQoL. The disease exerts a mild to moderate impact on productivity. Notably, psychological status shows a stronger association with loss of productivity. Higher HRQoL scores are strongly linked to reduced activity impairment and productivity. Emphasis should be on comprehensive care addressing physical, psychological, environmental and social aspects of HIV.
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Giwa, H.B., Oluwaseyi, A., Jamiu, M.O., Giwa, F.S. and Giwa, A. (2025) ‘A cross-sectional study on health-related quality of life and productivity loss in HIV/AIDS patients on ART’, Ilorin Journal of Science, 12(2), pp. 67–78. Available at: https://doi.org/10.54908/iljs.2025.12.02.006