Effects of UV, Red and Sun Light on the Stability of Phytochemicals, Antiradical and Antimicrobial Activity of Ocimum Gratissimum Linn. (Lamiaceae)

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dc.contributor.authorNjinga, NS; Bakare-Odunola, MT; Abdullahi, ST; Abdulmajeed, FF; Bello, HR; Saadu, RA; Aliyu, M; Egharevba, GO; Bamidele, OD; Shittu, AO
dc.date.accessioned2021-10-26T10:33:57Z
dc.date.available2021-10-26T10:33:57Z
dc.date.issued2020-12-01
dc.description.abstractThe content and stability of phenols, flavonoids, saponins and alkaloids in Ocimum gratissimum upon exposure to sunlight, red and ultra-violet (UV) radiation over a period of 168 h was investigated as well as the effect of irradiation on its antiradical and antimicrobial activities. Total phenolic, flavonoids, saponins and alkaloid contents were determined using standard methods while antiradical and antimicrobial analyses were determined using 1,1-diphenyl-2-picrylhydrazyl and agar diffusion methods, respectively. Exposure to sunlight significantly increased (p<0.05) the total phenolic and alkaloid contents. Ultra-violet and sun light significantly decreased the total flavonoid and saponin content, while all the three forms of radiation significantly increased antiradical activity as well as antimicrobial activity against Staphylococcus aureus. Red and UV light significantly increased the activity against S. aureus while UV light increased activity against Escherichia coli. These findings suggest photochemical instability with increased antiradical and antimicrobial activities of the methanol extracts of O. gratissimum after irradiation.en_US
dc.identifier.citation5. Njinga, N.S., Bakare-Odunola, M.T., Abdullahi, S.T., Abdulmajeed, F.F., Bello, H.R., Saadu, R.A., Aliyu, M., Egharevba, G.O., Bamidele, O.D. & Shittu, A.O. (2020): Effects of UV, Red and Sun Light on the Stability of Phytochemicals, Antiradical and Antimicrobial Activity of Ocimum Gratissimum Linn. (Lamiaceae). The East and Central African Journal of Pharmaceutical Sciences, 23 (3) : 121-133.en_US
dc.identifier.issn1026-552X
dc.identifier.urihttps://uilspace.unilorin.edu.ng/handle/20.500.12484/6738
dc.language.isoenen_US
dc.publisherSchool of Pharmacy, University of Nairobi, Nairobi, Kenyaen_US
dc.subjectOcimum gratissimumen_US
dc.subjectextract stabilityen_US
dc.subjectsunlighten_US
dc.subjectultraviolet lighten_US
dc.subjectantimicrobial assayen_US
dc.subjectantiradical activityen_US
dc.titleEffects of UV, Red and Sun Light on the Stability of Phytochemicals, Antiradical and Antimicrobial Activity of Ocimum Gratissimum Linn. (Lamiaceae)en_US
dc.typeArticleen_US
dc.typePreprinten_US

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