MOLECULAR IDENTIFICATION AND ANTIMICROBIAL ACTIVITY OF ENDOPHYTIC FUNGI ASPERGILLUS TAMARII (TRICHOMACEAE)

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dc.contributor.authorOgbole, OO
dc.contributor.authorAdebayo-Tayo, BC
dc.contributor.authorSalawu, KM
dc.contributor.authorOkoli, VC
dc.date.accessioned2019-10-21T13:28:59Z
dc.date.available2019-10-21T13:28:59Z
dc.date.issued2017-03
dc.description.abstractMicrobial drug resistance threatens the effective prevention and treatment of infectious diseases, this has prompted a continuous search for new and effective antibacterial agents from diverse sources including endophytic fungi of plants and mushroom. Aspergillus tamarii is an endophytic fungus that has been isolated from different plants and mushrooms such as Lycoperdon umbrinum. This study was undertaken to identify the endophytic fungi isolated from L. umbrinum and to evaluate the antimicrobial activity of the extract from the endophytic fungi. The endophytic fungus was identified as Aspergillus tamarii (strain SRRC 108818S) based on sequence data analysis of the internal transcribed spacer region of rDNA. The extract from Aspergillus tamarii had significant antibacterial activities on Salmonella typhi (ATCC33458), Staphylococcus aureus (ATCC6538), Bacillus subtilis (ATCC6633), Escherichia coli (ATCC25922), with zone of inhibitions of 15.5 ± 0.707, 14.5 ± 0.707, 14 ± 0.00 and 23 ± 1.414 respectively at the highest concentration of 200 mg/mL. The extract however, does not have any effect on Candida albicans at all tested concentration. Aspergillus tamarii is an endophytic fungus that could be a potential source of antibacterial agent.en_US
dc.identifier.urihttp://hdl.handle.net/123456789/2952
dc.language.isoenen_US
dc.publisherNigerian Journal of Pharmaceutical Sciencesen_US
dc.subjectAntibacterial activityen_US
dc.subjectAspergillus tamariien_US
dc.subjectEndophytic fungien_US
dc.subjectLycoperdon umbrinumen_US
dc.subjectMolecular identificationen_US
dc.titleMOLECULAR IDENTIFICATION AND ANTIMICROBIAL ACTIVITY OF ENDOPHYTIC FUNGI ASPERGILLUS TAMARII (TRICHOMACEAE)en_US
dc.typeArticleen_US

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