Anti-Ulcerogenic and Gastric Antisecretory Effects of Corchorus olitorius Extract in Male Albino Rats
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Date
2015-08
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Publisher
Taylor & Francis Informa Ltd Registered in England and Wales
Abstract
Anti-ulcerogenic and gastric anti-secretory activity of aqueous extract of Cochorus olitorius was investigated in HCl/ethanol and indomethacin-induced gastric lesions in male albino rats. Pre-treatment with aqueous extract (50, 100, or 200 mg.kg−1) orally for 2 weeks reduced ulcer formation, except those pre-treated with 50 mg.kg− in the indomethacin model. In both models, the decrease in gastric acid production was dose-dependent
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Keywords
Gastric acid,, Indomethacin