Anti-Ulcerogenic and Gastric Antisecretory Effects of Corchorus olitorius Extract in Male Albino Rats

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Date

2015-08

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Taylor & Francis Informa Ltd Registered in England and Wales

Abstract

Anti-ulcerogenic and gastric anti-secretory activity of aqueous extract of Cochorus olitorius was investigated in HCl/ethanol and indomethacin-induced gastric lesions in male albino rats. Pre-treatment with aqueous extract (50, 100, or 200 mg.kg−1) orally for 2 weeks reduced ulcer formation, except those pre-treated with 50 mg.kg− in the indomethacin model. In both models, the decrease in gastric acid production was dose-dependent

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Keywords

Gastric acid,, Indomethacin

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