Effect of packing on changes in erythrocyte osmotic fragility and malondialdehyde concentration in donkeys administered with ascorbic acid.

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dc.contributor.authorOlaifa, Folashade Helen
dc.contributor.authorAyo, Joseph Olusegun
dc.contributor.authorAmbali, Suleiman Folorunsho
dc.contributor.authorRekwot, Peter Ibrahim
dc.date.accessioned2020-01-30T11:11:16Z
dc.date.available2020-01-30T11:11:16Z
dc.date.issued2012
dc.descriptionNILen_US
dc.description.abstractExperiments were performed with the aim of investigating the effect of packing on erythrocyte osmotic fragility (EOF) and malondialdehyde (MDA) concentration in donkeys, and the effect of ascorbic acid (AA). Twelve apparently healthy donkeys raised under the traditional extensive system served as experimental subjects. Six donkeys administered orally with AA (200 mg/kg) and subjected to packing were used as experimental animals, whilst six others not administered with AA served as controls. Blood samples were collected pre- and post-packing from all the donkeys for the determination of MDA and EOF. At 0.3% Sodium Chloride (NaCl) concentration, the percentage haemolysis was 93.69% ± 2.21% in the control donkeys and the value was significantly (P < 0.05) higher than the value of 71.31% ± 8.33%, recorded in the experimental donkeys. The post-packing MDA concentration obtained in the control donkeys was 39.62 µmol ± 4.16 µmol, and was not significantly different (P > 0.05) from the value of 35.97 µmol ± 2.88 µmol recorded in the experimental donkeys. In conclusion, the increase in haemolysis obtained in the donkeys suggested that packing induced oxidative stress, which was ameliorated by AA administration.en_US
dc.description.sponsorshipNILen_US
dc.identifier.citation13en_US
dc.identifier.otherDOI: https://doi.org/10.4102/ojvr.v79i1.413
dc.identifier.urihttp://hdl.handle.net/123456789/3608
dc.language.isoenen_US
dc.publisherAgricultural Research Council, ARC-OVU and University of Pretoriaen_US
dc.subjectAscorbic aciden_US
dc.subjectdonkeyen_US
dc.subjecthaemolysisen_US
dc.subjectmalondialdehydeen_US
dc.subjectwork stressen_US
dc.titleEffect of packing on changes in erythrocyte osmotic fragility and malondialdehyde concentration in donkeys administered with ascorbic acid.en_US
dc.typeArticleen_US

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