AMEEN, OMGARUBA, TZUBAIR, MFBAKER, MTAROWOLO, BZYAKUBU, AO2022-11-092022-11-092022-04PRINT ISSN 1119-8362Electronic ISSN 1119-8362https://uilspace.unilorin.edu.ng/handle/20.500.12484/7874This research aims to investigate the antioxidant activity of the crude extract of endophytic fungi (T. harzianum) and to test for the presence of phytochemicals. Fungi isolated from the leaf and stem of endemic medicinal plant were extracted with ethyl acetate. The fungi extract was then investigated for its phytochemicals, antioxidants and active compounds through LC-MS. Some of the phytochemicals present in abundance include saponins, alkaloids, flavonoids, phenols, and steroids, with tanins and cardiac glycosides also present in reasonable amounts. Those compounds identified by LC-MS with antioxidant properties include inosine diphosphate, vigabatrin, isoamylnitrite, proline, trihexyphenidyl-N-oxide, N-methyl gabapentin, penbutolol, dextromoramide M2, solanidine, aceclidine, desethyleneciproflaxin, sapropterin and kinetin.enEndophytic fungiTrichoderma harzianumantioxidantsphytochemicalsLC-MSArticle