Williams, F.E.Adesoye, A.A.Jolayemi, E.T.Parakoyi, D.B.Awoyemi, A.O.Dominic, O.L.Kayode, O.O.2024-05-032024-05-0320154. Williams, F.E., Adesoye, A.A., Jolayemi, E.T., Parakoyi, D.B., Awoyemi, A.O., Dominic, O.L. & Kayode, O.O. (2015) Knowledge and Attitude towards TB-HIV co-infection among students of a tertiary institution in North-Central Nigeria. Centrepoint Journal (Science Edition). 21 (2): 157-172.https://uilspace.unilorin.edu.ng/handle/123456789/13544NoneTuberculosis and Human Immunodeficiency Virus (TB-HIV) co-infection poses a public health challenge to sustainable national development due to the burden of the disease. Lack of knowledge and poor attitude towards the disease especially in congregate setting, such as tertiary institutions contribute to its spread. The study examined the knowledge and attitude towards TB-HIV co-infection among students of Kwara State College of Education, Ilorin. It was a cross-sectional and non-interventional study using structured questionnaire tested for reliability (r = 0.99). Four hundred and five eligible students were interviewed using the questionnaire. Statistical Package for Social Sciences Version 17.00 was used for data entry and analysis. The findings revealed a mean score of 53.4% for knowledge about TB-HIV co-infection. The knowledge about the reciprocal interaction between TB and HIV was 40.2% while knowledge for laboratory diagnosis being difficult was 28.2%. Furthermore, the mean score for attitude was 45%. Only 30.0% of the respondents felt that prospective marital relationship should not be broken if laboratory tests are positive for TB-HIV co-infection. Significant differences were found between the level of education of the students and their knowledge of the difficulty of laboratory diagnosis of TB-HIV co-infection (p<0.05); and between the level of education and their attitudes towards breaking prospective marital relationship if the partner is diagnosed with TB-HIV co-infection (P<0.05). This study recommended that health education on diseases of public health importance should be included in the curriculum for tertiary education.enKnowledgeAttitudeTB-HIV co-infectionsReciprocal InteractionAntiretroviral and TB medicinesArticle