Ologele, ISalami, K. A.Ilutonmihi, O.Isiaka, G.Abraham, J. O.2023-09-062023-09-062021https://uilspace.unilorin.edu.ng/handle/20.500.12484/11736herbal medicine is the use of herbs or medicinal plants properties for the prevention and treatment of illnesses.' It takes the form of concoction, decoction and infusion. The researchers observed common usage of herbal medicines among residents of Odo-Otin Local Government Area, Osun State, Nigeria and there was a claimed of efficacy of these herbs despite not fully integrated in healthcare. The purpose of study therefore, was to investigate the perceived potency of; (i) candle bush flower (senna alata) and boundary tree leave (newboldia leavis) for the treatment of pile and diarrhea. A descriptive research design of the survey type was employed for this study. The population of the study comprised all herbal medicine users in Odo-Otin Local Government Area, Osun State, Nigeria. Multi-stage sampling procedure which consists of purposive and snowball sampling techniques used to select 384respondents for the study. A researchers developed questionnaire validated by three experts in the Department of Health Promotion and and Environmental Health Education, University of Ilorin, Nigeria was used for the study and tested for reliability using a split-half method. A reliability coefficient of 0.75 was obtained using obtained using the Spearman Brown Prophesy Formula. Relevant data collected by the researchers and three trained research assistants. Inferential statistics of Chi-square was used to test the hypotheses formulated for the study at 0.05 level of significance. The findings of the study indicated that, the use of candle bush flower was perceived as significantly potent for the treatment of pile because the calculated value of (25.21) greater than the table value of (21.03) at 12 degree of freedom, the use of boundary tree leaves was perceived as significantly potent for the treatment of diarrhea because the calculated value of (28.33) greater than the table value of (21.03) at b12 degree of freedom. The study concluded that candle bush flower and boundary tree leave are potency for the treatment of pile and diarrhea. Therefore, it was recommended that candle busy flower and boundary tree leave should be further subjected to NAFDAC test and if found effective, should be considered for the treatment of pile and diarrhea.PotencyHerbal-medicinesIllnessesTreatmentArticle