Bojuwoye, Matthew OlumuyiwaObateru, Olusegun AyodejiAliyu, Aminu MansaOkonkwo, Kenechukwu ChukwuemekaOgbu, Lawrence OgbonnayaOjimi, Olajumoke OlubusayoArinde OlufemiSafiu, Kamorudeen IsholaOlokoba, Abdulfatai Bamidele2024-04-172024-04-172023http://www.njghonweb.orghttps://uilspace.unilorin.edu.ng/handle/123456789/12204Background: Upper gastrointestinal bleeding (UGIB) is a common and potentially life-threatening condition. Oesophagogastroduodenoscopy (OGD) is an invaluable tool in the investigation and management of UGIB. Aim: We studied the spectrum of endoscopy findings among patients who were referred for OGD on account of UGIB. Methodology: This was a cross-sectional study of patients who had OGD done at the University of Ilorin Teaching Hospital on account of UGIB from year 2010 to 2022. Endoscopies were performed as per the standard protocol with diagnosis based on accepted criteria. Data were retrieved from the endoscopy register, entered into a spreadsheet, and analyzed using the Statistical Package for Social Sciences (SPSS) version 22. Categorical variables were compared using a Chi-square test and statistical significance set at P < 0.05. Results: A total of 1438 patients (mean age: 51.0 ± 16.4 years; age range, 10–100 years; 730 [50.8%] females) were included. Of these patients, 280 (19.5%) presented with UGIB. Peptic ulcers disease (PUD) 68 (24.3%) followed by gastritis 50 (17.9%), esophageal/gastric varices 42 (15.0%), gastroduodenitis 20 (7.1%) and gastric tumors 18 (6.4%) were the commonest causes of UGIB in the study population. Of the 68 cases of PUD, 43 were duodenal ulcers whereas 25 were gastric ulcers. The mean age of patients with UGIB was 51.0 ± 20.0 years and it was more common in males 187 (66.8%); P < 0.05. Conclusion: UGIB was more common in males and the most common cause of UGIB in our study population was PUDenEsophageal varicesgastric tumorsoesophagogastroduodenoscopypeptic ulcerOther