Dele-Ojo, B.F., Raimi, T.H., Fadare, J.O., Dada, S.A., Ajayi, E.A., Ajayi, D.D.,Ogunmodede, James AyodeleAjayi, A.O2023-05-212023-05-212021Pan African Medical Journal 39; 257:26201:1-11.https://uilspace.unilorin.edu.ng/handle/20.500.12484/10661Introduction: metabolic syndrome portends an increased risk of cardiovascular events and death. Evidence showed that healthcare workers are at higher risk of cardiovascular events because of their engagement in night-shift work. Therefore, this study determined the association between metabolic syndrome and healthcare work status in Ekiti State, Nigeria. Methods: this was a cross-sectional study involving 105 healthcare workers and 143 non-healthcare workers. The diagnosis of metabolic syndrome was made based on the International Diabetic Federation criteria: Abdominal obesity plus, any two of: elevated blood pressure ≥ 130/85 mmHg or previous diagnosis of hypertension on the use of antihypertensive medications; impaired fasting glucose; elevated triglycerides; and low HDL-cholesterol. Factors associated with metabolic syndrome were analysed using univariable and multivariable analysis. Results: men comprised 37.9% of the study population and the mean age was 42.1 ± 9.7 years. The prevalence of metabolic syndrome was similar in both groups (HCWs-29.5% vs non-HCWs- 28.0%, p-value=0.789); overall prevalence was 28.6%. Abdominal obesity, elevated total cholesterol and elevated LDL-cholesterol occurred more frequently in HCWs than in non-HCWs: (68.6% vs 55.2%, p-value=0.034; 65.7% vs 39.2%, p-value= < 0.001 and 50.5 vs 28.7%; p-value < 0.001) respectively. Female sex (aOR:3.67, 95% CI: 1.74-7.45; p < 0.001) and obesity (aOR:4.39, 95% CI: 2.31-8.37; p < 0.001) were associated with metabolic syndrome. Conclusion: a similar prevalence of metabolic syndrome was observed in the healthcare workers and the non- healthcare workers. However, abdominal obesity, elevated total cholesterol and elevated LDL-cholesterol occurred more frequently in healthcare workers than in non- healthcare workersMetabolic syndrome, cardiovascular diseases, night shift, healthcare workers, abdominal obesity, elevated cholesterolArticle