A. O. SHITTU, H. O. OLAWUMI, B. A. ISSA, C. NWABUISI, I. A. DUROTOYE, A. D. YUSSUF, P. O AJIBOYE, O. A. ADEGUNLOYE, D. SULYMAN and A. K. SALAMI2023-06-052023-06-052014-03-10Shittu, A.O., Olawumi, H.O., Issa, B.A., Fadeyi, A., Nwabuisi, C., Durotoye, I.A., Yussuf, A.D., Ajiboye, P.O., Adegunloye, O.A., Sulyman, D. & Salami, A.K. (2014): Risk Factors and Sero-Prevalence of Hepatitis B Surface Antigen amongst Blood Donors in University of Ilorin Teaching Hospital, Ilorin, Nigeria. East Africa Medical Journal. 91(2): 57-61.https://uilspace.unilorin.edu.ng/handle/20.500.12484/10952Background: Availability of safe blood and blood products for transfusion is increasingly difficult globally, especially in developing countries because of high prevalence of Transfusion Transmissible Infections. Objectives: To determine the prevalence of HBsAg among blood donors and to evaluate the socioeconomic, demographic and medical factors associated with its infection. Materials and method: a prospective study whereby 350 consecutive blood donors were recruited. 2 ml of venous blood was collected aseptically from the ante-cubital vein and subjected to serological test for HBsAg. Results: High prevalence rate 10.9% was recorded. All the donors reactive to HBsAg were males (38,100%) with a mean age of 30.7±8.02 years, while 55.3%, 44.7%, 5.3%, 42%, 47.4%, 5.3% of them were single, married, primary school graduate, secondary school graduate, tertiary school graduate and illiterate respectively with 36.8%, 23.7%, 39.5% and0% been unemployed, civil servants/professionals, skilled artisans and business/petty traders. The commonest risk factor was multiple sexual partners 55.3%, followed by extra marital affairs 13.2%, tattooing 10.5%, previous blood transfusion 5.2%, previous surgery 2.6% and sex trading 2.6%. Conclusion: Active public enlightenment programs and sstrict blood donation selection criteria need to be put in place in order to provide safe blood and blood products for transfusion.enArticle