Omotoso, G.OAlabi, A.SOyabambi, A.O2021-06-092021-06-092013Omotoso, et al.: Effects of albendazole on the testeshttps://uilspace.unilorin.edu.ng/handle/20.500.12484/6059The testicular cytoarchitectural effects of albendazole administration were studied in adult Wistar rats. Materials and Methods: The animals were grouped into three groups, with six (6) rats per group. While animals in the control group A were given water, the treatment groups B and C received 15 mg/kg and 30 mg/kg respectively of albendazole orally for three consecutive days. The animals were sacrificed by cervical dislocation about 24 hours after drug administration, and the testes removed, fixed in 10% formal saline and processed for histological consideration, using Haematoxylin and Eosin stains.Results: Varying degrees of histological changes were noticed in the seminiferous tubules, which were marked in the group that received the higher dose of the drug. Conclusion: These structural distortions and degenerations of testicular tissues that occurred after albendazole administration are dose-dependent, and could affect reproductive functions in malesenAlbendazolehistologytestesWistar rats