Quantification of in situ granulation-induced changes in pre-compression, solubility, dose distribution and intrinsic in vitro release characteristics of ibuprofen-cationic dextran conjugate crystanules

Abioye, Amos OlusegunKola-Mustapha, AdeolaChi, George TangyieIlya, Sunday2018-03-212018-03-21201415http://hdl.handle.net/123456789/154enMelt in-situ granulation-crystallizationMechanism of densification, , ,Dose distributionMechanism of solubilizationMechanism of dissolution,Solubility-dissolution correlationQuantification of in situ granulation-induced changes in pre-compression, solubility, dose distribution and intrinsic in vitro release characteristics of ibuprofen-cationic dextran conjugate crystanulesArticle