Hamid, A. A.Negi, A. S.Zubair, M. F.Oguntoye, S. O.Aiyelaagbe, O. O2018-02-222018-02-222015CPJ 2015001/211012141-3819http://hdl.handle.net/123456789/108Ethyl acetate and methanol extracts of Turraea vogelli leaves exhibited cytotoxic activity on leukaemia carcinoma K562 with IC50 values 85.00 and 85.22 μg/mL respectively. Isolation of the extracts afforded Tetradec-7-enoic acid (1), pentadec-1-ene (2), ethyl tridec-7-enoate (3), β-sitosterol (4) and stigmasterol (5). The structures of these compounds were characterised by IR, ID and 2D NMR and Mass spectroscopy, and supported with literature data. Compounds 1 and 4 exhibited antiproliferative activity against K562 tumor cell lines with IC50 of 57.27 and 27.56 μg/mL respectively. All isolated compounds exhibited low cytotoxicity against WRL and MCF-7 tumor cell lines.enTurraea vogelli,ethyl tridec-7-enoatestigmasterol,β-sitosterol,antiproliferative activity,Article