Adesina, K.T., Saka, A., Isiaka-Lawal, S.A., Adesiyun, O.O., Gobir, A., Olarinoye, A.O. & Ezeoke,G.G.2024-05-132024-05-132018Kikelomo T. Adesina, Aishat Saka, Salamat A. Isiaka-Lawal, Omotayo O. Adesiyun, A. Gobir, Adebunmi. O. Olarinoye, and Grace G. Ezeoke, (2018) “Knowledge, Practice and Acceptability of HPV Vaccine by Mothers of Adolescent Girls in Ilorin, Nigeria,” Sudan Journal of Medical Sciences, vol. 13 (2018), issue no. 1, 33–49. DOI 10.18502/sjms.v13i1.1687DOI 10.18502/sjms.v13i1.1687https://uilspace.unilorin.edu.ng/handle/123456789/14116Background: Human Papilloma Virus (HPV) is a sexually transmitted cause of carcinoma of the cervix. An important determinant of the success of a primary preventive strategy like HPV vaccination is the knowledge and willingness of parents to vaccinate adolescents before sexual debut. Materials and methods of study: A cross sectional descriptive survey of mothers of girls in 8 secondary schools in Ilorin was carried out from February to April 2015. Schools were selected using multi staged sampling. Descriptive and inferential statistics were performed with Chi Square and ANOVA. Results: There were 470 questionnaires returned for analysis out of 600, giving aresponse rate of 78.3%. One hundred and sixty-one (34.3%) knew HPV to be sexually transmitted infection and 40.4% knew it was the cause of cervical cancer. While 35.1% were aware of HPV vaccine, only 1.9% had ever vaccinated their children. Less than half (44.9%) were willing to vaccinate their children. Women with good knowledge of HPV and cervical cancer were more willing to vaccinate their children than women with poor knowledge (P <0.001). Conclusion: There is poor knowledge of HPV and practice of vaccination among mothers in llorin. Willingness of mothers to vaccinate their daughters is suboptimal. Mother’s knowledge is an important determinant of HPV vaccination of adolescents. Adolescent girls’ vaccine, Ilorin HowenHuman Papilloma virusHPV vaccineprepubertal HPV vaccinationArticle