Prevalence of chronic kidney disease in patients with type 2 diabetes mellitus attending a secondary care hospital in north central Nigeria

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Date

2021

Journal Title

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Volume Title

Publisher

Journal of Pharmaceutical Research, Development and Practice,

Abstract

ABSTRACT Worldwide, Chronic Kidney Disease (CKD) is a public health problem that is associated with adverse outcomes of kidney failure, diseases of the cardiovascular system and untimely death. The purpose of this study was to determine the prevalence of chronic kidney disease in type 2 diabetes mellitus (DM) patients and to determine kidney staging on the basis of estimated glomerular filtration rate (eGFR) values. One hundred and twenty (120) patients were recruited for the study (mean age 54.7 ±14.701). This study was a prospective cross sectional study among out-patients with Diabetes mellitus in north central Nigeria. A validated questionnaire was used to capture socio-demographics. Informed consent was obtained from each patient and blood samples were collected in an EDTA vacutainer, after which the blood samples were sent to PATHCARE diagnostic center, to determine the serum creatinine and eGFR levels.Most of the subjects were female (75.0%) while only 25.0% were males. More than one half(67.5%) of the subjects have Stage I, 21.7% have Stage 2, 7.5% were on Stage 3, 1.7% on Stage 4 and 1.7% of the subjects have Stage 5 kidney disease.The prevalence of CKD among the type 2 Diabetes Mellitus patients studiedwas 10.8%.There is a need for studies with larger sample size. Routine eGFR assessment after 3 months in subjects with eGFRless than60 mL/min/1.7 m2should be emphazised.

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Keywords

Chronic Kidney disease (CKD), Diabetes mellitus, estimated glomerular filtration rate (eGFR)

Citation

2. Aliyu, F.O;Olorunfemi, O .T, Bello S.I, Jamiu M.O, Abdulazeez I.F, Williams F.E& Abdulbaki. M (2021). Prevalence of chronic kidney disease in patients with type 2 diabetes mellitus attending a secondary care hospital in north central Nigeria.Journal of Pharmaceutical Research, Development and Practice,,5(1)036-042.Published by Faculty of Pharmaceutical Sciences, University of Ilorin.

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